Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.55 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.55 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12900254 | 1.00 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL2143637 | 0.80 | TRIM24 (0.60) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL31607554 | 0.80 | TRIM24 (0.60) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL31302783 | 0.75 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL19518384 | 0.75 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL21623871 | 0.75 | BRPF1 (0.58) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL17150712 | 0.75 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL12865280 | 0.75 | TRIM24 (0.55) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL31049280 | 0.75 | HTR2A (0.56) | TRIM24TRIM33BRPF1ARHTR2A | |
| SCHEMBL23658612 | 0.75 | GPR84 (0.58) | DYRK1AAXLPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221684-A | Method for preparing quinoxaline derivative through HFIP-promoted defluorination cyclization reaction of difluoro carbene reagent | 陕西科技大学 | 2024-06-21 | — | — | CN | disclosed |