Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 3/20 | 0.32 |
| ▸ | CA5A | P35218 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.32 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986360 | 1.00 | PRKCA (0.34) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL4374202 | 1.00 | PRKCA (0.34) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL5744890 | 0.82 | PRKCA (0.38) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL8034413 | 0.82 | PRKCA (0.35) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL7797765 | 0.82 | PRKCA (0.38) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL3121259 | 0.82 | PRKCA (0.35) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL8376902 | 0.82 | PRKCA (0.38) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL3482282 | 0.81 | PRKCA (0.37) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL13277097 | 0.78 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL29974888 | 0.77 | PRKCA (0.36) | PRKCAPRKD3PRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174065-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | ZADEC APS (DK) | 2019-01-08 | — | — | US | disclosed |
| US-20160083411-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2016-03-24 | — | — | US | disclosed |
| US-9221860-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | ZADEC APS (DK) | 2015-12-29 | — | — | US | disclosed |
| EP-2625184-B1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2014-10-01 | — | — | EP | disclosed |
| US-20130310331-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2013-11-21 | — | — | US | disclosed |
| EP-2625184-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | Zadec ApS (DK) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012045363-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2012-04-12 | — | — | WO | disclosed |
| US-7141394-B2 | More stable analog of isopropyl thiogalactoside for induction of protein expression | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-11-28 | — | — | US | disclosed |
| US-20040224390-A1 | More stable analog of isopropylthiogalactoside for induction of protein expression | IOWA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2004-11-11 | — | — | US | disclosed |
| WO-2004094445-A1 | A MORE STABLE ANALOG OF ISO-PROPYLTHIOGALACTOSIDE FOR INDUCTION OF PROTEIN EXPRESSION | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174065-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | PC, SLC5A1, SLC5A2 | PRKCA 469/4885PRKD3 2020/4885PRKCG 411/4885 |
| US-20160083411-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | PC, SLC5A1, SLC5A2 | PRKCA 469/4885PRKD3 2020/4885PRKCG 411/4885 |
| US-20040224390-A1 | More stable analog of isopropylthiogalactoside for induction of protein expression | PPIG, B3GAT3, PPIC | PRKCA 2464/4885PRKD3 3331/4885PRKCG 702/4885 |
| US-20130310331-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | PC, SLC5A1, SLC5A2 | PRKCA 469/4885PRKD3 2020/4885PRKCG 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.