Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15695018 | 0.75 | ESR1 (0.77) | ESR1ESR2KDM4EMAPTGPR3 | |
| SCHEMBL3483852 | 0.75 | ESR1 (0.77) | ESR1ESR2KDM4EMAPTGPR3 | |
| SCHEMBL15592583 | 0.74 | ESR1 (0.57) | ESR1ESR2GPR3CHEK1MAOA | |
| SCHEMBL29368441 | 0.70 | GPR3 (0.75) | ESR1ESR2GPR3CHEK1MAOA | |
| SCHEMBL31472931 | 0.70 | GPR3 (0.75) | ESR1ESR2GPR3CHEK1MAOA | |
| SCHEMBL472539 | 0.70 | GPR3 (0.75) | ESR1ESR2GPR3CHEK1MAOA | |
| SCHEMBL12955756 | 0.70 | ESR1 (0.53) | ESR1ESR2GPR3CHEK1MAOA | |
| SCHEMBL10633969 | 0.70 | ALDH1A1 (0.55) | KDM4EMAPTMAOAALDH1A1TDP1 | |
| SCHEMBL12935854 | 0.69 | ESR1 (0.55) | ESR1ESR2GPR3CHEK1MAOA | |
| SCHEMBL12081669 | 0.67 | ESR1 (0.68) | ESR1ESR2GPR3CHEK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835632-B2 | Methods to increase the photostability of dyes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-09-16 | — | — | US | disclosed |
| US-8835632-B2 | Methods to increase the photostability of dyes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-09-16 | — | — | US | disclosed |
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | PTMS, ACP1, SNRPE | ESR1 3063/4885ESR2 3815/4885KDM4E 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.