SCHEMBL472539

SCHEMBL472539

O=C1c2ccccc2S(=O)(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.75
CHEK1 O14757 3/20 0.61
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
MAOA P21397 3/20 0.58
CDC25B P30305 1/20 0.55
PSMD14 O00487 1/20 0.51
ALDH1A1 P00352 2/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
GPR35 Q9HC97 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31472931 1.00 GPR3 (0.75) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL29368441 1.00 GPR3 (0.75) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL29481 0.86 GPR3 (1.00) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL29387122 0.86 GPR3 (1.00) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL10945035 0.82 MAOA (0.57) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL17954672 0.82 MAOA (0.54) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL12796758 0.82 CHEK1 (0.59) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL16900704 0.82 MEN1 (0.62) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL5972625 0.82 GPR3 (0.52) GPR3CHEK1MEN1KMT2AL3MBTL1
SCHEMBL5800591 0.82 CHEK1 (0.59) GPR3CHEK1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112010847-A Solution-processable organic electroluminescent diode main body material and application thereof 南京工业职业技术大学 2020-12-01 CN claimed
US-20200227664-A1 ELECTROLUMINESCENT DEVICE AND LIGHT-EMITTING LAYER AND APPLICATION THEREOF GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-07-16 US claimed
EP-3247773-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2019-10-02 EP claimed
US-20140357633-A1 COMPOUNDS FOR INHIBITING THE INTERACTION OF BCL2 WITH BINDING PARTNERS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2014-12-04 US claimed
EP-2794592-A1 COMPOUNDS FOR INHIBITING THE INTERACTION OF BCL2 WITH BINDING PARTNERS Novartis AG (CH) 2014-10-29 EP claimed
WO-2013096060-A1 COMPOUNDS FOR INHIBITING THE INTERACTION OF BCL2 WITH BINDING PARTNERS NOVARTIS AG (CH) 2013-06-27 WO claimed
US-8367745-B2 Includes alkaline earth metal oxide as acidity neutralization stabilizer; quick setting, mechanical strength; repairing prosthesis GC CORPORATION (JP) 2013-02-05 US claimed
US-7678843-B2 Dental restorative material composition GC CORPORATION (JP) 2010-03-16 US claimed
US-5770638-A CONSISTS OF TETRAHYDROFURFURYL METHACRYLATE, ONE OR MORE METHACRYLATE HAVING ATLEAST ONE DOUBLE BOND SELECTED FROM DI-2-METHACRYLOXYETHYL-2,2-4-TRIMETHYLHEXAMETHYLENE DICARBAMATE AND OTHER ACRYLATED CARBAMATE AND PHOTOINITIATORS GC CORPORATION (JP) 1998-06-23 US claimed
JP-10168427-A None JP disclosed
JP-62034980-A None JP disclosed
JP-10168427-A None JP disclosed
CN-122080034-A Polycyclic aromatic compound and organic electroluminescent element 2026-05-26 CN disclosed
CN-122059973-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2026-05-19 CN disclosed
US-4377579-A ANTIALLERGENS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-03-22 US disclosed
US-4177257-A ANTIANAPHYLACTIC AGENTS BURROUGHS WELLCOME CO. (US) 1979-12-04 US disclosed
US-4145350-A ANTIALLERGENS, TETRAZOLYL- SUBSTITUTED BURROUGHS WELLCOME CO. (US) 1979-03-20 US disclosed
US-4103015-A TRICYCLIC THIOXANTHONE-10,10-DIOXIDES BURROUGHS WELLCOME CO. (US) 1978-07-25 US disclosed
US-4103015-A TRICYCLIC THIOXANTHONE-10,10-DIOXIDES BURROUGHS WELLCOME CO. (US) 1978-07-25 US disclosed
US-4012499-A USED IN THE RELIEF AND PROPHYLAXIS OF ALLERGIC CONDITIONS BURROUGHS WELLCOME CO. (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140357633-A1 COMPOUNDS FOR INHIBITING THE INTERACTION OF BCL2 WITH BINDING PARTNERS BCL2, BCL2A1, BCL2L1 GPR3 2272/4885CHEK1 1450/4885MEN1 2831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.