Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12901032 | 0.88 | CHAT (0.41) | GPR3ESR1ESR2KDM4EMAPT | |
| SCHEMBL12901133 | 0.82 | CHAT (0.47) | GPR3ESR1ESR2KDM4EMAPT | |
| SCHEMBL7473289 | 0.78 | GPR3 (0.44) | GPR3ESR1ESR2KDM4EMAPT | |
| SCHEMBL7473284 | 0.78 | GPR3 (0.44) | GPR3ESR1ESR2KDM4EMAPT | |
| SCHEMBL12901031 | 0.74 | — | — | |
| SCHEMBL12715302 | 0.72 | ESR1 (0.49) | GPR3ESR1ESR2KDM4EMAPT | |
| SCHEMBL4567101 | 0.71 | ESR1 (0.51) | GPR3ESR1ESR2MIFKMT2A | |
| SCHEMBL13019511 | 0.71 | ESR1 (0.51) | GPR3ESR1ESR2MIFKMT2A | |
| SCHEMBL7467947 | 0.71 | GPR3 (0.50) | GPR3ESR1ESR2MIFKMT2A | |
| SCHEMBL8792998 | 0.69 | GPR3 (0.33) | GPR3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835632-B2 | Methods to increase the photostability of dyes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-09-16 | — | — | US | disclosed |
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | PTMS, ACP1, SNRPE | GPR3 3232/4885ESR1 3063/4885ESR2 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.