SCHEMBL8792998

SCHEMBL8792998

O=S1(=O)C(C=CC=Cc2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)=C(O)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.33
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7473284 0.74 GPR3 (0.44) GPR3ESR1ESR2
SCHEMBL7473289 0.74 GPR3 (0.44) GPR3ESR1ESR2
SCHEMBL12901145 0.69 GPR3 (0.36) GPR3ESR1ESR2
SCHEMBL12901032 0.68 CHAT (0.41) GPR3ESR1ESR2
SCHEMBL12715302 0.68 ESR1 (0.49) GPR3ESR1ESR2
SCHEMBL4567101 0.68 ESR1 (0.51) GPR3ESR1ESR2
SCHEMBL13019511 0.68 ESR1 (0.51) GPR3ESR1ESR2
SCHEMBL7467947 0.67 GPR3 (0.50) GPR3ESR1ESR2
SCHEMBL12901133 0.62 CHAT (0.47) GPR3ESR1ESR2
SCHEMBL79976 0.61 PDE5A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0771796-A1 Substituted S-triazines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-07 EP disclosed