SCHEMBL12901189

SCHEMBL12901189

CCCCCCCCC1=CCC(O)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 7/20 0.41
PTGS2 P35354 3/20 0.34
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSPD1 P10809 1/20 0.34
ADRB3 P13945 1/20 0.34
HTR2C P28335 1/20 0.34
HSPE1 P61604 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18676864 1.00 SPHK1 (0.41) SPHK1PTGS2ESR1ADRA2AADORA3
SCHEMBL13782307 0.79 SPHK1 (0.33) SPHK1PTGS2ESR1ADRA2AADORA3
SCHEMBL25000895 0.79 SPHK1 (0.35) SPHK1EPHX1EPHX2SPHK2
SCHEMBL9414358 0.78 ESR2 (0.41) SPHK1ALDH1A1CYP3A4CES2ALOX15
SCHEMBL2525156 0.76 S1PR5 (0.43) ALDH1A1LMNAALOX15CYP1B1
SCHEMBL9414353 0.74 ALDH1A1 (0.40) ALDH1A1KDM4ELMNAALOX15CYP1B1
SCHEMBL27826327 0.73 PTGS2 (0.39) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL9414347 0.72 ALDH1A1 (0.53) ALDH1A1CYP3A4ALOX15CYP1B1
SCHEMBL2969313 0.71 SPHK1 (0.35) SPHK1ALDH1A1CES2ALOX15CYP1B1
SCHEMBL6900524 0.71 CES2 (0.32) ALDH1A1CES2ALOX15CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011021257-A1 METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER, METHOD FOR PRODUCING ISOCYANATE USING N-SUBSTITUTED CARBAMIC ACID ESTER, AND COMPOSITION FOR TRANSFERRING AND STORING N-SUBSTITUTED CARBAMIC ACID ESTER CONTAINING N-SUBSTITUTED CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND 旭化成ケミカルズ株式会社 (JP) 2011-02-24 WO disclosed