Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577529 | 0.78 | NPSR1 (0.47) | NPSR1ALDH1A1KDM4ENPC1TDP1 | |
| SCHEMBL12215252 | 0.73 | TACR1 (0.41) | NPSR1ALDH1A1KDM4ENPC1TDP1 | |
| SCHEMBL3987626 | 0.73 | POLB (0.55) | ALDH1A1NPC1POLBMEN1KMT2A | |
| SCHEMBL6972604 | 0.72 | NPSR1 (0.61) | NPSR1L3MBTL1POLBTSHRFKBP1A | |
| SCHEMBL21091374 | 0.72 | NPSR1 (0.61) | NPSR1L3MBTL1POLBTSHRFKBP1A | |
| SCHEMBL9280388 | 0.72 | NPSR1 (0.61) | NPSR1L3MBTL1POLBTSHRFKBP1A | |
| SCHEMBL5898614 | 0.72 | NPSR1 (0.61) | NPSR1L3MBTL1POLBTSHRFKBP1A | |
| SCHEMBL12191427 | 0.72 | TACR1 (0.42) | NPSR1ALDH1A1KDM4ENPC1TDP1 | |
| SCHEMBL22110413 | 0.72 | DPP4 (0.50) | NPSR1KDM4EPOLBDPP4 | |
| SCHEMBL8178849 | 0.72 | DPP4 (0.50) | NPSR1KDM4EPOLBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020913-A2 | CYCLODEPSIPEPTIDE ANTIVIRAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2011-02-24 | — | — | WO | disclosed |