SCHEMBL12901995

SCHEMBL12901995

CC(=O)c1csc([C@@H]2O[C@H](CO)[C@H](O)C2O)n1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PYGL P06737 2/20 0.52
SLC5A2 P31639 10/20 0.42
UMPS P11172 1/20 0.40
SLC28A3 Q9HAS3 2/20 0.40
GALR3 O60755 1/20 0.39
NR2F2 P24468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tiazofurin SCHEMBL4453888 0.87 PYGL (0.53) PYGLUMPS
Tiazofurin SCHEMBL4287 0.87 PYGL (0.53) PYGLUMPS
SCHEMBL7832887 0.87 PYGL (0.53) PYGLSLC5A2UMPSGALR3NR2F2
Tiazofurin SCHEMBL23264566 0.87 PYGL (0.53) PYGLUMPS
Tiazofurin SCHEMBL2883659 0.87 PYGL (0.53) PYGLUMPS
Tiazofurin SCHEMBL23848843 0.87 PYGL (0.53) PYGLUMPS
Tiazofurin SCHEMBL13109276 0.87 PYGL (0.53) PYGLUMPS
Tiazofurin SCHEMBL1651851 0.87 PYGL (0.53) PYGLUMPS
Tiazofurin SCHEMBL2883657 0.87 PYGL (0.53) PYGLUMPS
Tiazofurin SCHEMBL7169632 0.87 PYGL (0.53) PYGLUMPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110033422-A1 TREATMENTS FOR FLAVIVIRIDAE VIRUS INFECTION SCHERING CORPORATION 2011-02-10 US disclosed
US-7524831-B2 Treatments for Flaviviridae virus infection SCHERING CORPORATION (US) 2009-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110033422-A1 TREATMENTS FOR FLAVIVIRIDAE VIRUS INFECTION HAVCR2, EIF2AK2, HNRNPC PYGL 1084/4885SLC5A2 4145/4885UMPS 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.