Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.74 |
| ▸ | F13A1 | P00488 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | FASN | P49327 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 6/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | F7 | P08709 | 2/20 | 0.32 |
| ▸ | F3 | P13726 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cerulenin SCHEMBL20528755 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTPTGS1F13A1THRB | |
| Cerulenin SCHEMBL8678332 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTPTGS1F13A1THRB | |
| Cerulenin SCHEMBL28576416 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTPTGS1F13A1THRB | |
| Cerulenin SCHEMBL4450603 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTPTGS1F13A1THRB | |
| Cerulenin SCHEMBL3183350 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTPTGS1F13A1THRB | |
| Cerulenin SCHEMBL41207 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTPTGS1F13A1THRB | |
| Cerulenin SCHEMBL8716153 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTPTGS1F13A1THRB | |
| Cerulenin SCHEMBL10387308 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTPTGS1F13A1THRB | |
| SCHEMBL9453465 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTPTGS1F13A1THRB | |
| SCHEMBL9453468 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTPTGS1F13A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110033422-A1 | TREATMENTS FOR FLAVIVIRIDAE VIRUS INFECTION | SCHERING CORPORATION | 2011-02-10 | — | — | US | disclosed |
| US-7816339-B2 | Treatments for Flaviviridae virus infection | SCHERING CORPORATION (US) | 2010-10-19 | — | — | US | disclosed |
| US-7592315-B2 | Peptide viral entry inhibitors | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-20090209483-A1 | TREATMENTS FOR FLAVIVIRIDAE VIRUS INFECTION | SCHERING CORPORATION | 2009-08-20 | — | — | US | disclosed |
| US-7524831-B2 | Treatments for Flaviviridae virus infection | SCHERING CORPORATION (US) | 2009-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110033422-A1 | TREATMENTS FOR FLAVIVIRIDAE VIRUS INFECTION | HAVCR2, EIF2AK2, HNRNPC | ALDH1A1 464/4885MAPT 4147/4885PTGS1 2431/4885 |
| US-20090209483-A1 | TREATMENTS FOR FLAVIVIRIDAE VIRUS INFECTION | HAVCR2, EIF2AK2, HNRNPC | ALDH1A1 464/4885MAPT 4147/4885PTGS1 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.