Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1240529 | 0.84 | ALOX12 (0.76) | ALOX12KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL12905180 | 0.84 | BRAF (0.54) | ALOX12KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL12906678 | 0.82 | ALOX12 (0.44) | ALOX12KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL12905264 | 0.82 | PPP1CA (0.71) | ALOX12KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL12906466 | 0.80 | HSP90AA1 (0.58) | ALOX12KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL12905270 | 0.80 | BRAF (0.55) | ALOX12KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL12905266 | 0.80 | ALDH1A1 (0.55) | ALOX12KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL12905979 | 0.80 | ALOX12 (0.56) | ALOX12KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL12905938 | 0.79 | LMNA (0.49) | ALOX12KDM4ENPSR1ALDH1A1MAPT | |
| SCHEMBL12905220 | 0.78 | BRAF (0.52) | ALOX12KDM4ENPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020886-A1 | NOVEL QUINOLINE-HEPCIDINE ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-02-24 | — | — | WO | disclosed |