Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14798295 | 1.00 | ADAMTS4 (0.58) | ADAMTS4HSD11B1KMT2AKEAP1NFE2L2 | |
| SCHEMBL10911759 | 0.86 | AGER (0.59) | ADAMTS4KEAP1NFE2L2ALDH1A1MMP9 | |
| SCHEMBL16894216 | 0.84 | ADAMTS4 (0.50) | ADAMTS4KMT2AKEAP1NFE2L2GAA | |
| SCHEMBL16894214 | 0.84 | ADAMTS4 (0.50) | ADAMTS4KMT2AKEAP1NFE2L2GAA | |
| SCHEMBL12908023 | 0.83 | ADAMTS4 (0.49) | ADAMTS4HSD11B1KMT2AKEAP1NFE2L2 | |
| SCHEMBL4569289 | 0.82 | ADAMTS4 (0.53) | ADAMTS4HSD11B1KMT2AAPOBEC3GESR1 | |
| SCHEMBL8446545 | 0.82 | ADAMTS4 (0.48) | ADAMTS4KEAP1NFE2L2ADAMTS5ALDH1A1 | |
| SCHEMBL26679674 | 0.80 | CA12 (0.59) | MMP9MMP2MMP13 | |
| SCHEMBL26679672 | 0.80 | CA12 (0.59) | MMP9MMP2MMP13 | |
| SCHEMBL14805422 | 0.80 | LOX (0.45) | ADAMTS4HSD11B1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827088-B | It is used as the derivative of the pyridyl alkyl alcohol of 1 phenyl 2 of phosphodiesterase inhibitors | 奇斯药制品公司 | 2017-10-13 | — | — | CN | disclosed |
| US-7872021-B2 | LXR receptor modulators | LABORATORIES FOURNIER S.A. (FR) | 2011-01-18 | — | — | US | disclosed |
| US-20070099960-A1 | LXR receptor modulators | LABORATOIRES FOURNIER S.A. (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099960-A1 | LXR receptor modulators | NR1H2, NR1H3, PPARD | ADAMTS4 4842/4885HSD11B1 78/4885KMT2A 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.