Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.85 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.85 |
| ▸ | NPC1 | O15118 | 2/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.85 |
| ▸ | RAB9A | P51151 | 2/20 | 0.85 |
| ▸ | XBP1 | P17861 | 1/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | SCN1A | P35498 | 1/20 | 0.74 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.74 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.70 |
| ▸ | CRHBP | P24387 | 1/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAP1A | P62834 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12908956 | 0.93 | ALDH1A1 (0.93) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL14043530 | 0.92 | ALDH1A1 (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL13947382 | 0.92 | ALDH1A1 (0.86) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL29374346 | 0.92 | ALDH1A1 (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL12908957 | 0.88 | ALDH1A1 (0.84) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL15502881 | 0.87 | ALDH1A1 (0.89) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| Alpha-Bungarotoxin SCHEMBL14106557 | 0.85 | SCN1A (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL13947366 | 0.85 | ALDH1A1 (0.91) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL10130542 | 0.85 | ALDH1A1 (0.87) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL10159481 | 0.85 | ALDH1A1 (0.91) | ALDH1A1NPSR1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009479-A1 | Stimulating Neuronal Growth Using Brevetoxins | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009479-A1 | Stimulating Neuronal Growth Using Brevetoxins | BDNF, GAP43, GRN | ALDH1A1 3844/4885NPSR1 1425/4885NPC1 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.