Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | XBP1 | P17861 | 1/20 | 1.00 |
| ▸ | SCN1A | P35498 | 1/20 | 0.86 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.86 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.86 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | CRHBP | P24387 | 1/20 | 0.66 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAP1A | P62834 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14043530 | 1.00 | ALDH1A1 (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL13947382 | 0.93 | ALDH1A1 (0.86) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| Alpha-Bungarotoxin SCHEMBL29366348 | 0.93 | SCN1A (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| Alpha-Bungarotoxin SCHEMBL29386702 | 0.93 | SCN1A (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| Alpha-Bungarotoxin SCHEMBL29374938 | 0.93 | SCN1A (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| Alpha-Bungarotoxin SCHEMBL29381923 | 0.93 | SCN1A (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| Alpha-Bungarotoxin SCHEMBL14043478 | 0.93 | SCN1A (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| Brevetoxin B SCHEMBL869360 | 0.93 | SCN1A (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| Alpha-Bungarotoxin SCHEMBL14106557 | 0.93 | SCN1A (1.00) | ALDH1A1NPSR1NPC1MAPTMAPK1 | |
| SCHEMBL12908960 | 0.92 | ALDH1A1 (0.85) | ALDH1A1NPSR1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12350260-B2 | Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning | UNIVERSITE DE BRETAGNE OCCIDENTALE (FR) | 2025-07-08 | — | — | US | disclosed |
| CN-111138447-B | B-group hapten, artificial antigen and monoclonal antibody of Gymnodinium breve toxin, and preparation method and application thereof | 国家海洋环境监测中心 | 2022-09-06 | — | — | CN | disclosed |
| US-20220193048-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | UNIVERSITE DE BRETAGNE OCCIDENTALE (FR) | 2022-06-23 | — | — | US | disclosed |
| EP-3946332-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | Université de Bretagne Occidentale (FR) | 2022-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193048-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | PRSS12, TPSB2, F2RL1 | ALDH1A1 2394/4885NPSR1 76/4885NPC1 2326/4885 |
| US-12350260-B2 | Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning | PRSS12, TPSB2, F2RL1 | ALDH1A1 2394/4885NPSR1 76/4885NPC1 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.