Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CCR9 | P51686 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TCF4 | P15884 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12909349 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL11930669 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL12909483 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL12909350 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL12909355 | 0.78 | CYP2C9 (0.47) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL11930656 | 0.78 | CCR9 (0.57) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL12909353 | 0.78 | LMNA (0.50) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL12909348 | 0.77 | FFAR4 (0.48) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL10248298 | 0.76 | LMNA (0.56) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 | |
| SCHEMBL11930653 | 0.76 | CCR9 (0.62) | ALDH1A1CYP1A2HPGDHSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021523-A1 | ARYL SULFONAMIDES | CHEMOCENTRYX, INC. (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021523-A1 | ARYL SULFONAMIDES | CCR9, CCR1, CCR2 | ALDH1A1 1655/4885CYP1A2 1855/4885HPGD 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.