Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146370 | 1.00 | MAPK1 (0.39) | MAPK1RECQLHRH3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL28928210 | 0.98 | MAPK1 (0.38) | MAPK1RECQLHRH3CHRM2CHRM1 | |
| SCHEMBL22618471 | 0.83 | — | — | |
| SCHEMBL19447710 | 0.81 | MAPK1 (0.35) | MAPK1RECQLCHRM2CHRM1CHRM3 | |
| SCHEMBL24039255 | 0.80 | MAPK1 (0.37) | MAPK1RECQLHRH3CHRM2CHRM1 | |
| SCHEMBL5728913 | 0.78 | MAPK1 (0.37) | MAPK1RECQLHRH3CHRM2CHRM1 | |
| SCHEMBL29770711 | 0.78 | — | — | |
| SCHEMBL31375005 | 0.78 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL31645127 | 0.77 | PKM (0.53) | MAPK1RECQLCHRM2CHRM1CHRM3 | |
| SCHEMBL3547830 | 0.77 | MAPK1 (0.32) | MAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011013785-A1 | NITROGEN-CONTAINING SPIRO-RING COMPOUND AND MEDICINAL USE OF SAME | 日本たばこ産業株式会社 (JP) | 2011-02-03 | — | — | WO | disclosed |