Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12909511 | 1.00 | MAPK1 (0.39) | MAPK1RECQLHRH3CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL28928210 | 0.98 | MAPK1 (0.38) | MAPK1RECQLHRH3CHRM2CHRM1 | |
| SCHEMBL22618471 | 0.83 | — | — | |
| SCHEMBL19447710 | 0.81 | MAPK1 (0.35) | MAPK1RECQLCHRM2CHRM1CHRM3 | |
| SCHEMBL24039255 | 0.80 | MAPK1 (0.37) | MAPK1RECQLHRH3CHRM2CHRM1 | |
| SCHEMBL5728913 | 0.78 | MAPK1 (0.37) | MAPK1RECQLHRH3CHRM2CHRM1 | |
| SCHEMBL29770711 | 0.78 | — | — | |
| SCHEMBL31375005 | 0.78 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL31645127 | 0.77 | PKM (0.53) | MAPK1RECQLCHRM2CHRM1CHRM3 | |
| SCHEMBL3547830 | 0.77 | MAPK1 (0.32) | MAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673900-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof | JAPAN TOBACCO INC. (JP) | 2023-06-13 | — | — | US | disclosed |
| US-11339181-B2 | Crystalline forms of a Janus kinase inhibitor | JAPAN TOBACCO INC. (JP) | 2022-05-24 | — | — | US | disclosed |
| US-11312728-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and co-crystals thereof | JAPAN TOBACCO INC. (JP) | 2022-04-26 | — | — | US | disclosed |
| US-10822354-B2 | Method for producing 7h-pyrrolo[2, 3-d]pyrimidine derivative and intermediate thereof | JAPAN TOBACCO INC. (JP) | 2020-11-03 | — | — | US | disclosed |
| US-20200165269-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND CO-CRYSTALS THEREOF | SHIONOGI & CO., LTD. (JP) | 2020-05-28 | — | — | US | disclosed |
| EP-3321271-A1 | METHOD FOR PRODUCING 7H-PYRROLO[2, 3-D]PYRIMIDINE DERIVATIVE AND INTERMEDIATE THEREOF | Japan Tobacco, Inc. (JP) | 2018-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312728-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and co-crystals thereof | JAK1, JAK3, JAK2 | MAPK1 244/4885RECQL 4097/4885HRH3 2139/4885 |
| US-11673900-B2 | Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof | JAK1, JAK3, JAK2 | MAPK1 73/4885RECQL 4349/4885HRH3 2602/4885 |
| US-11339181-B2 | Crystalline forms of a Janus kinase inhibitor | JAK1, JAK3, JAK2 | MAPK1 77/4885RECQL 4154/4885HRH3 1996/4885 |
| US-10822354-B2 | Method for producing 7h-pyrrolo[2, 3-d]pyrimidine derivative and intermediate thereof | JAK1, JAK3, JAK2 | MAPK1 98/4885RECQL 4660/4885HRH3 2376/4885 |
| US-20200165269-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND CO-CRYSTALS THEREOF | JAK1, JAK3, JAK2 | MAPK1 244/4885RECQL 4097/4885HRH3 2139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.