SCHEMBL1290972

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1290970	1.00	HSPB1 (0.63)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL21628069	0.87	HSPB1 (0.60)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL11685383	0.86	HSPB1 (0.59)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL2858921	0.85	HSPB1 (0.54)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL2858917	0.85	HSPB1 (0.54)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL23797981	0.84	HSPB1 (0.55)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL30391879	0.83	HSPB1 (0.55)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL4690573	0.83	MEN1 (0.79)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL20932230	0.83	HSPB1 (0.82)	HSPB1MAPTMEN1KMT2ANPSR1
	SCHEMBL2851303	0.82	HSPB1 (0.49)	HSPB1MAPTMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.