SCHEMBL12911819

SCHEMBL12911819

Cc1cc(Cl)cc(C(=O)N(C)C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 3/20 0.38
▸ CARM1 Q86X55 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ PDE4B Q07343 3/20 0.36
▸ MALT1 Q9UDY8 1/20 0.35
▸ GPBAR1 Q8TDU6 1/20 0.35
▸ TRPV1 Q8NER1 2/20 0.35
▸ EDNRA P25101 1/20 0.34
▸ KLKB1 P03952 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL951072 0.94 KDM4E (0.37) F10CARM1KDM4EMEN1ALDH1A1
SCHEMBL10028786 0.93 F10 (0.39) F10CARM1KDM4EMEN1ALDH1A1
SCHEMBL11960059 0.92 F10 (0.38) F10CARM1KDM4EMEN1ALDH1A1
SCHEMBL10028782 0.92 CARM1 (0.37) F10CARM1KDM4EMEN1ALDH1A1
SCHEMBL13209133 0.91 PDE4B (0.41) F10CARM1KDM4EMEN1ALDH1A1
SCHEMBL17204815 0.91 PDE4B (0.37) F10CARM1KDM4EMEN1ALDH1A1
SCHEMBL17205424 0.91 PDE4B (0.37) F10CARM1KDM4EMEN1ALDH1A1
SCHEMBL13072902 0.90 F10 (0.37) F10CARM1KDM4EMEN1ALDH1A1
SCHEMBL12529000 0.90 PDE4B (0.34) F10KDM4EMEN1ALDH1A1MAPT
SCHEMBL782368 0.90 CARM1 (0.39) F10CARM1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT F10 3713/4885CARM1 2140/4885KDM4E 2028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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