Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | XBP1 | P17861 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12912453 | 0.93 | KDM4E (0.47) | KDM4ERAD52SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12912461 | 0.87 | NLRP3 (0.60) | KDM4ESMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL16433652 | 0.85 | ALDH1A1 (0.47) | KDM4ESMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL12912466 | 0.81 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2NPC1ALDH1A1HSD17B10 | |
| SCHEMBL12912463 | 0.80 | NLRP3 (0.57) | KDM4ESMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL12912528 | 0.79 | CA1 (0.43) | KDM4ESMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL12716528 | 0.77 | KDM4E (0.43) | KDM4EKMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL12912501 | 0.77 | ALDH1A1 (0.43) | KDM4ESMN1; SMN2NPC1ALDH1A1HSD17B10 | |
| SCHEMBL9976945 | 0.77 | PDE10A (0.47) | KDM4ESMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL13128467 | 0.76 | KDM4E (0.46) | KDM4ESMN1; SMN2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | NUDC, TYR, NUDT1 | KDM4E 427/4885RAD52 2206/4885SMN1; SMN2 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.