Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12912458 | 0.91 | KDM4E (0.54) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL12912436 | 0.87 | PDE10A (0.48) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL9976908 | 0.86 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL9611740 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL24811942 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL16433652 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL12912534 | 0.78 | RAB9A (0.48) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL9976969 | 0.78 | HDAC1 (0.52) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL13128467 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL9976955 | 0.77 | HDAC1 (0.51) | KDM4EALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945724-B2 | Nitrogen-containing heterocyclic derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-8945724-B2 | Nitrogen-containing heterocyclic derivative and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110012092-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | NUDC, TYR, NUDT1 | KDM4E 427/4885ALDH1A1 1960/4885LMNA 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.