SCHEMBL12912946

SCHEMBL12912946

c1ccc(-c2c[nH]c(-c3ccc(-c4scc(-c5ccccc5)c4-c4ccccc4)c4ncccc34)c2-c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 5/20 0.36
SKP2 Q13309 5/20 0.36
GLO1 Q04760 2/20 0.36
PDPK1 O15530 1/20 0.34
DYRK1A Q13627 2/20 0.33
CHEK1 O14757 1/20 0.33
EGFR P00533 1/20 0.33
KDR P35968 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP1A2 P05177 1/20 0.33
CAMKK2 Q96RR4 1/20 0.33
IMPDH2 P12268 2/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
COMT P21964 1/20 0.32
PARP1 P09874 1/20 0.32
DYRK1B Q9Y463 1/20 0.32
LMNA P02545 1/20 0.32
TOP1 P11387 1/20 0.32
CDC7 O00311 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12912895 0.88 CKS1B (0.42) CKS1BSKP2GLO1PDPK1CYP17A1
SCHEMBL12912926 0.86 CKS1B (0.43) CKS1BSKP2GLO1DYRK1ACHEK1
SCHEMBL12912965 0.80 HASPIN (0.39) DYRK1ACYP17A1CYP1A2IMPDH2MAPK1
SCHEMBL12912936 0.77 PARP1 (0.38) PDPK1CHEK1EGFRKDRCYP17A1
SCHEMBL12912938 0.75 CYP2A6 (0.35) PDPK1CHEK1EGFRKDRCYP17A1
SCHEMBL12912964 0.74 PDPK1 (0.35) PDPK1DYRK1AKDRIMPDH2MAPK1
SCHEMBL12912944 0.73 DYRK1A (0.36) PDPK1DYRK1ACAMKK2IMPDH2LMNA
SCHEMBL12912933 0.73 IMPDH2 (0.38) PDPK1CHEK1EGFRKDRIMPDH2
SCHEMBL12912935 0.71 MEN1 (0.35) CHEK1EGFRKDRIMPDH2MAPK1
SCHEMBL12912945 0.70 IMPDH2 (0.33) PDPK1CYP1A2IMPDH2MAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed