SCHEMBL12912964

SCHEMBL12912964

c1ccc(-c2c[nH]c(-c3cnc(-c4scc(-c5ccccc5)c4-c4ccccc4)cn3)c2-c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.35
LMNA P02545 1/20 0.35
DYRK1A Q13627 3/20 0.34
CDK8 P49336 3/20 0.34
TGFBR1 P36897 1/20 0.34
AXL P30530 1/20 0.34
TNIK Q9UKE5 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CDK2 P24941 3/20 0.33
AURKA O14965 2/20 0.33
JAK2 O60674 2/20 0.33
CDK1 P06493 2/20 0.33
FGFR1 P11362 2/20 0.33
MARK3 P27448 2/20 0.33
MARK2 Q7KZI7 2/20 0.33
PLK4 O00444 1/20 0.33
ROCK2 O75116 1/20 0.33
PRKD3 O94806 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12912944 0.88 DYRK1A (0.36) PDPK1LMNADYRK1ACDK8TGFBR1
SCHEMBL12912908 0.86 ALOX5AP (0.38) PDPK1LMNADYRK1ANPC1RAB9A
SCHEMBL12912928 0.86 CDK8 (0.42) DYRK1ACDK8TGFBR1AXLTNIK
SCHEMBL12912933 0.78 IMPDH2 (0.38) PDPK1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL12912936 0.77 PARP1 (0.38) PDPK1LMNACDK8AXLTNIK
SCHEMBL12912896 0.76 HPGDS (0.36) PDPK1LMNADYRK1ANPC1RAB9A
SCHEMBL12912965 0.75 HASPIN (0.39) DYRK1ACDK8AXLTNIKRAB9A
SCHEMBL12912938 0.75 CYP2A6 (0.35) PDPK1LMNANPC1KDRIMPDH2
SCHEMBL12912945 0.75 IMPDH2 (0.33) PDPK1LMNAIMPDH2MAPK1
SCHEMBL12912918 0.75 AXL (0.42) DYRK1ACDK8TGFBR1AXLTNIK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed