SCHEMBL12912908

SCHEMBL12912908

c1ccc(-c2csc(-c3cnc(-c4scc(-c5ccccc5)c4-c4ccccc4)cn3)c2-c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.38
FEN1 P39748 1/20 0.38
DAPK3 O43293 1/20 0.38
PRKD3 O94806 1/20 0.38
MAP4K4 O95819 1/20 0.38
ABL1 P00519 1/20 0.38
NTRK1 P04629 1/20 0.38
LCK P06239 1/20 0.38
CSF1R P07333 1/20 0.38
RET P07949 1/20 0.38
MET P08581 1/20 0.38
PDGFRB P09619 1/20 0.38
FGFR1 P11362 1/20 0.38
PDGFRA P16234 1/20 0.38
PRKACA P17612 1/20 0.38
FLT1 P17948 1/20 0.38
LTK P29376 1/20 0.38
KDR P35968 1/20 0.38
MAP2K2 P36507 1/20 0.38
MAPK8 P45983 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12912896 0.88 HPGDS (0.36) ALOX5APFEN1DAPK3PRKD3MAP4K4
SCHEMBL12912964 0.86 PDPK1 (0.35) PRKD3MAP4K4FGFR1PRKACAFLT1
SCHEMBL6632155 0.83 ALDH1A1 (0.37) LMNASMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL6036925 0.81 BACE1 (0.41) DAPK3PRKD3MAP4K4ABL1NTRK1
Phosphine SCHEMBL28718427 0.79 BACE1 (0.41) DAPK3PRKD3MAP4K4ABL1NTRK1
SCHEMBL12912887 0.77 BACE1 (0.40) DAPK3PRKD3MAP4K4ABL1NTRK1
SCHEMBL6741582 0.77 SMN1; SMN2 (0.51) LMNASMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL12860033 0.76 RAB9A (0.48) LMNASMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL12912944 0.76 DYRK1A (0.36) DYRK1ALMNAPDPK1SMN1; SMN2NPC1
SCHEMBL12912883 0.76 BACE1 (0.36) DAPK3PRKD3MAP4K4ABL1NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-7871714-B2 Polymer, electroluminescent device, and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-01-18 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed
US-20090102374-A1 POLYMER, ELECTROLUMINESCENT DEVICE, AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-04-23 US disclosed