Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14207166 | 0.85 | AKR1B1 (0.37) | HTR6AKR1B1CES1PDE7APGR | |
| SCHEMBL12946119 | 0.82 | HTR6 (0.31) | HTR6MGAT2 | |
| SCHEMBL13773277 | 0.79 | LMNA (0.38) | HTR6AKR1B1CES1PDE7APGR | |
| SCHEMBL9076137 | 0.69 | CHEK1 (0.44) | HTR6AKR1B1CES1MAPTPGR | |
| SCHEMBL24690661 | 0.66 | PGR (0.53) | AKR1B1CES1PDE7APGRMAOB | |
| SCHEMBL21624206 | 0.66 | PGR (0.35) | AKR1B1PGR | |
| SCHEMBL30832442 | 0.65 | POLB (0.30) | — | |
| SCHEMBL9379504 | 0.64 | BRD4 (0.45) | HTR6AKR1B1CES1MAPTPDE7A | |
| SCHEMBL3596379 | 0.63 | MGAT2 (0.37) | MAPTPGRMGAT2MEN1KMT2A | |
| SCHEMBL7170898 | 0.63 | CSNK1G1 (0.45) | AKR1B1MAPTMGAT2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647781-B2 | Redox fuel cells | ACAL ENERGY LIMITED (GB) | 2014-02-11 | — | — | US | disclosed |
| US-8647781-B2 | Redox fuel cells | ACAL ENERGY LIMITED (GB) | 2014-02-11 | — | — | US | disclosed |
| US-20130126443-A1 | CARBON SUPPORTED TETRAAMIDO MACROCYCLIC LIGAND CATALYTIC ACTIVATORS AND METHODS FOR MAKING THE SAME | CARNEGIE MELLON UNIVERSITY (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2235781-B1 | REDOX FUEL CELLS | ACAL ENERGY LTD (GB) | 2012-10-24 | — | — | EP | disclosed |
| US-20110014532-A1 | REDOX FUEL CELLS | ACAL ENERGY LIMITED (GB) | 2011-01-20 | — | — | US | disclosed |
| WO-2009093082-A1 | REDOX FUEL CELLS | ACAL ENERGY LIMITED (GB) | 2009-07-30 | — | — | WO | disclosed |