SCHEMBL129136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17084550	1.00	TDP1 (0.53)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL9972408	0.93	TDP1 (0.61)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL17637585	0.91	TDP1 (0.59)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL8777321	0.90	ALDH1A1 (0.53)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL15158802	0.90	ALDH1A1 (0.53)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL4201315	0.89	TDP1 (0.53)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL17084551	0.88	TDP1 (0.67)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL17763252	0.87	ALDH1A1 (0.55)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL21168984	0.86	ALDH1A1 (0.56)	TDP1ALDH1A1MAPK1L3MBTL1LMNA
	SCHEMBL16594584	0.86	TDP1 (0.61)	TDP1ALDH1A1MAPK1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.