Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | VDR | P11473 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12913695 | 0.85 | GAA (0.49) | MEN1KMT2AVDRCYP19A1ESR1 | |
| SCHEMBL12913705 | 0.85 | VDR (0.45) | MEN1KMT2AVDRCYP19A1DRD3 | |
| SCHEMBL12913709 | 0.83 | VDR (0.43) | MEN1KMT2AVDRCYP1A2HSD17B10 | |
| SCHEMBL21160631 | 0.78 | HTR1A (0.41) | MEN1KMT2AVDRDRD2HTR5A | |
| SCHEMBL12913699 | 0.77 | GAA (0.45) | MEN1KMT2AVDRHTR5AESR1 | |
| SCHEMBL21160440 | 0.76 | VDR (0.38) | MEN1KMT2AVDRCYP1A2GAA | |
| SCHEMBL21160442 | 0.74 | PKM (0.43) | MEN1KMT2AVDRCYP1A2CYP1A1 | |
| SCHEMBL15892650 | 0.73 | CYP1A2 (0.38) | VDRDRD3CYP1A2 | |
| SCHEMBL15892645 | 0.73 | CYP1A2 (0.44) | VDRDRD2DRD4CYP1A2HSD17B10 | |
| SCHEMBL12913706 | 0.73 | CYP1A2 (0.55) | MEN1KMT2AVDRCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872079-B2 | Naphthoxazine composition | SEKISUI CHEMICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-7872079-B2 | Naphthoxazine composition | SEKISUI CHEMICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090240006-A1 | A curable mixture of a naphthazine compound having a terminal aromatic ring bearing an hydroxyl group and a epoxy resins; high heat resistance; hardness; tensile strength;mechanical strength; dimensional stability; moldings; electronics; spacecraft; aircraft;automobile parts | CASE WESTERN RESERVE UNIVERSITY (US) | 2009-09-24 | — | — | US | disclosed |
| US-20090240006-A1 | A curable mixture of a naphthazine compound having a terminal aromatic ring bearing an hydroxyl group and a epoxy resins; high heat resistance; hardness; tensile strength;mechanical strength; dimensional stability; moldings; electronics; spacecraft; aircraft;automobile parts | CASE WESTERN RESERVE UNIVERSITY (US) | 2009-09-24 | — | — | US | disclosed |