Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.68 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1291512 | 1.00 | GPR119 (0.68) | GPR119ADAMTS5AKR1B1CNR1PIM1 | |
| SCHEMBL15260780 | 1.00 | GPR119 (0.68) | GPR119ADAMTS5AKR1B1CNR1PIM1 | |
| SCHEMBL1291666 | 0.92 | GPR119 (0.72) | GPR119ADAMTS5AKR1B1PIM1PIM2 | |
| SCHEMBL1291669 | 0.92 | GPR119 (0.72) | GPR119ADAMTS5AKR1B1PIM1PIM2 | |
| SCHEMBL1292032 | 0.92 | GPR119 (0.72) | GPR119ADAMTS5AKR1B1PIM1PIM2 | |
| SCHEMBL1291598 | 0.91 | GPR119 (0.68) | GPR119ADAMTS5AKR1B1PIM1PIM2 | |
| SCHEMBL1291601 | 0.91 | GPR119 (0.68) | GPR119ADAMTS5AKR1B1PIM1PIM2 | |
| SCHEMBL15260484 | 0.91 | GPR119 (0.68) | GPR119ADAMTS5AKR1B1PIM1PIM2 | |
| SCHEMBL1291533 | 0.87 | GPR119 (0.69) | GPR119ADAMTS5AKR1B1CNR1PIM1 | |
| SCHEMBL15260285 | 0.87 | GPR119 (0.69) | GPR119ADAMTS5AKR1B1CNR1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625177-B1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LTD (IN) | 2015-07-29 | — | — | EP | claimed |
| US-8785463-B2 | GPR 119 agonists | CADILA HEALTHCARE LIMITED (IN) | 2014-07-22 | — | — | US | claimed |
| US-20130252980-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2013-09-26 | — | — | US | claimed |
| EP-2625177-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2013-08-14 | — | — | EP | claimed |
| WO-2012046249-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2012-04-12 | — | — | WO | claimed |
| EP-2625177-B1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LTD (IN) | 2015-07-29 | — | — | EP | disclosed |
| US-8785463-B2 | GPR 119 agonists | CADILA HEALTHCARE LIMITED (IN) | 2014-07-22 | — | — | US | disclosed |
| US-20130252980-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2013-09-26 | — | — | US | disclosed |
| EP-2625177-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012046249-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252980-A1 | NOVEL GPR 119 AGONISTS | GPR119, GPR27, GPR4 | GPR119 1/4885ADAMTS5 4245/4885AKR1B1 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.