Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458831 | 0.94 | HTR3A (0.50) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL435619 | 0.86 | HTR3A (0.59) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL315186 | 0.86 | HTR3A (0.58) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL19181804 | 0.85 | DRD2 (0.46) | HTR3ASLC18A3DRD2SLC2A1CYP2C9 | |
| SCHEMBL12056679 | 0.83 | HTR3A (0.44) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL19621345 | 0.83 | KDM1A (0.45) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL19502455 | 0.83 | ESR2 (0.59) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL9181738 | 0.83 | HTR3A (0.44) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL9955456 | 0.83 | ESR2 (0.57) | HTR3ASLC18A3DRD2SLC2A1MEN1 | |
| SCHEMBL9181742 | 0.83 | HTR3A (0.44) | HTR3ASLC18A3DRD2SLC2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284148-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2011-02-16 | — | — | EP | disclosed |