Tolyl Boronic Acid

Tolyl Boronic Acid

SCHEMBL129197

Cc1ccc(B(O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 1.00
LPL P06858 3/20 1.00
LIPG Q9Y5X9 3/20 1.00
ORAI1 Q96D31 1/20 0.68
ORAI2 Q96SN7 1/20 0.68
ORAI3 Q9BRQ5 1/20 0.68
TRPV6 Q9H1D0 1/20 0.68
ENPP2 Q13822 6/20 0.55
CA1 P00915 3/20 0.52
TSHR P16473 1/20 0.52
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
ACHE P22303 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MGLL Q99685 2/20 0.48
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tolyl Boronic Acid SCHEMBL5600068 1.00 CA2 (1.00) CA2LPLLIPGORAI1ORAI2
Tolyl Boronic Acid SCHEMBL8889893 0.97 CA2 (0.94) CA2LPLLIPGORAI1ORAI2
Tolyl Boronic Acid SCHEMBL19268206 0.97 CA2 (0.94) CA2LPLLIPGORAI1ORAI2
Tolyl Boronic Acid SCHEMBL1992708 0.97 CA2 (0.94) CA2LPLLIPGORAI1ORAI2
SCHEMBL1853563 0.92 CA2 (0.84) CA2LPLLIPGORAI1ORAI2
Tolyl Boronic Acid SCHEMBL3395642 0.92 CA2 (0.84) CA2LPLLIPGORAI1ORAI2
Tolyl Boronic Acid SCHEMBL20694970 0.89 CA2 (0.80) CA2LPLLIPGORAI1ORAI2
SCHEMBL2309007 0.87 LPL (0.76) CA2LPLLIPGORAI1ORAI2
Tolyl Boronic Acid SCHEMBL21180370 0.87 CA2 (0.76) CA2LPLLIPGORAI1ORAI2
SCHEMBL257916 0.85 CA2 (0.73) CA2LPLLIPGORAI1ORAI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8643 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886736-B 2-Indolyl-3-imine indoline derivative, preparation method and application thereof Suzhou Highfine Biotech Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12478615-B2 Prolyl hydroxylase inhibitors and methods of use AKEBIA THERAPEUTICS, INC. (US) 2025-11-25 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250177537-A1 AN ANTIBIOTIC, METHOD OF PREPARATION AND METHOD OF TREATMENT THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-06-05 US claimed
CN-120058757-A Synthesis method of methyl iminodiacetic acid borate compound 上海泰坦科技股份有限公司 2025-05-30 CN claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-120025359-A Phenylboronic acid-based P/N/B-containing halogen-free flame retardant, and preparation method and application thereof 江南大学 2025-05-23 CN claimed
CN-119978389-A Boron-containing oligomer for aging-resistant high-transparency addition-type silicon rubber, and preparation method and application thereof 中国科学院化学研究所 2025-05-13 CN claimed
US-20250134860-A1 NOVEL COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING BACTERIAL INFLAMMATION AND INFLAMMASOME-MEDIATED DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT QUORUM BIO CO., LTD. (KR) 2025-05-01 US claimed
WO-2025073833-A1 OPTIMIZED PROCESS FOR THE PREPARATION OF IOPAMIDOL BRACCO IMAGING SPA (IT) 2025-04-10 WO claimed
EP-1107982-A1 REVERSIBLE BORONATE COMPLEXES OF 1,2-$i(CIS)-DIOL CYCLIC-PEPTIDES Eli Lilly & Company (US) 2001-06-20 EP claimed
US-6124476-A SUZUKI CROSS-COUPLING REACTIONS. PHOSPHINOBENZALDEHYDES AND ACETALS SYMYX TECHNOLOGIES, INC. (US) 2000-09-26 US claimed
EP-0765331-B1 OXABOROLES AND SALTS THEREOF, AND THEIR USE AS BIOCIDES AVECIA LTD (GB) 2000-08-09 EP claimed
US-6051251-A Liposome loading method using a boronic acid compound ALZA CORPORATION (US) 2000-04-18 US claimed
WO-2000012540-A1 REVERSIBLE BORONATE COMPLEXES OF 1,2-CIS-DIOL CYCLIC-PEPTIDES ELI LILLY AND COMPANY (US) 2000-03-09 WO claimed
US-5880188-A PROTECTING MEDIUM SUSCEPTIBLE TO MICROBIAL ATTACK BY TREATING WITH SPECIFIED OXABOROLE COMPOUND ZENECA LIMITED (GB) 1999-03-09 US claimed
US-5756804-A Homogeneous process for carrying out cross-coupling reactions HOECHST AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed
EP-0765331-A1 OXABOROLES AND SALTS THEREOF, AND THEIR USE AS BIOCIDES ZENECA LIMITED (GB) 1997-04-02 EP claimed
WO-1995033754-A1 OXABOROLES AND SALTS THEREOF, AND THEIR USE AS BIOCIDES ZENECA LIMITED (GB) 1995-12-14 WO claimed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO claimed