Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.84 |
| ▸ | LPL | P06858 | 3/20 | 0.84 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.84 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.59 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.59 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.59 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tolyl Boronic Acid SCHEMBL5600068 | 0.92 | CA2 (1.00) | CA2LPLLIPGORAI1ORAI2 | |
| Tolyl Boronic Acid SCHEMBL129197 | 0.92 | CA2 (1.00) | CA2LPLLIPGORAI1ORAI2 | |
| Tolyl Boronic Acid SCHEMBL1992708 | 0.89 | CA2 (0.94) | CA2LPLLIPGORAI1ORAI2 | |
| Tolyl Boronic Acid SCHEMBL8889893 | 0.89 | CA2 (0.94) | CA2LPLLIPGORAI1ORAI2 | |
| Tolyl Boronic Acid SCHEMBL19268206 | 0.89 | CA2 (0.94) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL1853563 | 0.84 | CA2 (0.84) | CA2LPLLIPGORAI1ORAI2 | |
| Tolyl Boronic Acid SCHEMBL20694970 | 0.82 | CA2 (0.80) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL2309007 | 0.80 | LPL (0.76) | CA2LPLLIPGORAI1ORAI2 | |
| Tolyl Boronic Acid SCHEMBL21180370 | 0.80 | CA2 (0.76) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL257916 | 0.78 | CA2 (0.73) | CA2LPLLIPGORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417140-B1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2014-11-26 | — | — | EP | disclosed |
| US-8349839-B2 | Inhibitors of HIV replication | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20100261714-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261714-A1 | INHIBITORS OF HIV REPLICATION | RTF2, POLR1A, REV1 | CA2 4448/4885LPL 4735/4885LIPG 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.