Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15265867 | 0.84 | KMT2A (0.40) | KMT2AMEN1RAD52NPSR1 | |
| SCHEMBL15264940 | 0.79 | KMT2A (0.37) | KMT2AMEN1POLBNPSR1 | |
| SCHEMBL1292197 | 0.78 | NCOA1 (0.36) | KMT2AMEN1POLBRAD52 | |
| SCHEMBL7535208 | 0.78 | MAPK1 (0.50) | KMT2AMEN1RAD52 | |
| SCHEMBL7539138 | 0.74 | SMN1; SMN2 (0.48) | KMT2AMEN1 | |
| SCHEMBL29221428 | 0.73 | STING1 (0.51) | STING1KMT2AMEN1POLBSCD | |
| SCHEMBL7534511 | 0.73 | ALDH1A1 (0.51) | KMT2AMEN1POLBNPSR1 | |
| SCHEMBL22887133 | 0.72 | STING1 (0.65) | STING1KMT2AMEN1SCD | |
| SCHEMBL1282433 | 0.72 | KMT2A (0.37) | STING1KMT2AMEN1POLBRAD52 | |
| SCHEMBL6068038 | 0.72 | LMNA (0.49) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828257-A1 | ANTIBACTERIAL COMPOUNDS | Biota Europe Ltd (GB) | 2015-01-28 | — | — | EP | disclosed |
| WO-2013138860-A1 | ANTIBACTERIAL COMPOUNDS | BIOTA EUROPE LIMITED (GB) | 2013-09-26 | — | — | WO | disclosed |
| EP-2625178-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | Biota Europe Ltd (GB) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |