Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 13/20 | 0.79 |
| ▸ | PARP1 | P09874 | 5/20 | 0.79 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.79 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.79 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.69 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | GABRP | O00591 | 2/20 | 0.65 |
| ▸ | GABRD | O14764 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424789 | 0.88 | TNKS (1.00) | TNKSPARP1TNKS2PARP2HDAC6 | |
| SCHEMBL29369345 | 0.88 | TNKS (1.00) | TNKSPARP1TNKS2PARP2HDAC6 | |
| SCHEMBL12941166 | 0.83 | CYP3A4 (0.74) | TNKSPARP1TNKS2PARP2HDAC6 | |
| SCHEMBL12940901 | 0.82 | GABRP (0.65) | TNKSPARP1TNKS2PARP2HDAC6 | |
| SCHEMBL12941168 | 0.82 | GABRP (0.72) | TNKSPARP1TNKS2PARP2HDAC6 | |
| Flavone SCHEMBL23645524 | 0.82 | TNKS (0.90) | TNKSPARP1TNKS2PARP2HDAC6 | |
| SCHEMBL14302733 | 0.81 | TNKS (0.64) | TNKSPARP1TNKS2PARP2HDAC6 | |
| SCHEMBL38655536 | 0.81 | FTO (0.70) | TNKSPARP1TNKS2PARP2HDAC6 | |
| SCHEMBL127446 | 0.80 | TNKS (1.00) | TNKSPARP1TNKS2PARP2PLA2G2A | |
| SCHEMBL29773081 | 0.80 | TNKS (1.00) | TNKSPARP1TNKS2PARP2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277595-A2 | Compounds for immunopotentiation | Novartis Vaccines and Diagnostics, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |