Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 8/20 | 0.49 |
| ▸ | THRB | P10828 | 11/20 | 0.47 |
| ▸ | THRA | P10827 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903046 | 0.88 | THRB (0.49) | PCNATHRBTHRALMNAHSD17B10 | |
| SCHEMBL1526094 | 0.80 | THRB (0.68) | PCNATHRBTHRALMNAHSD17B10 | |
| SCHEMBL19695859 | 0.72 | THRB (0.58) | PCNATHRBTHRALMNAHSD17B10 | |
| SCHEMBL14826122 | 0.72 | MTNR1A (0.45) | PCNATHRBTHRALMNAHSD17B10 | |
| SCHEMBL19696744 | 0.70 | THRB (0.76) | PCNATHRBTHRALMNAHSD17B10 | |
| SCHEMBL19679560 | 0.70 | PCNA (0.62) | PCNATHRBTHRALMNAHSD17B10 | |
| SCHEMBL19679558 | 0.70 | THRB (0.62) | PCNATHRBTHRALMNAHSD17B10 | |
| Thyromedan SCHEMBL29385284 | 0.70 | PCNA (0.46) | PCNATHRBTHRALMNAHSD17B10 | |
| SCHEMBL6859639 | 0.69 | PCNA (0.50) | PCNATHRBTHRALMNAHSD17B10 | |
| SCHEMBL6471833 | 0.69 | MTNR1A (0.45) | LMNAHSD17B10PPARGPOLBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361453-B2 | Iodinated polymers | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110022161-A1 | IODINATED POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-01-27 | — | — | US | disclosed |