Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170711 | 0.88 | GAA (0.39) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL12945027 | 0.84 | GAA (0.38) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL12945149 | 0.82 | GAA (0.36) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL20170807 | 0.82 | GAA (0.48) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL12945098 | 0.81 | GAA (0.37) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL10222587 | 0.78 | GAA (0.39) | GAAOPRD1 | |
| SCHEMBL12646332 | 0.77 | OPRM1 (0.51) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL18458096 | 0.77 | GAA (0.44) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL10222583 | 0.77 | OPRM1 (0.33) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL20170595 | 0.77 | GAA (0.36) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009015-A1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT INC. (US) | 2011-01-20 | — | — | WO | disclosed |