Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170821 | 0.83 | GAA (0.36) | GAA | |
| SCHEMBL20170851 | 0.82 | GAA (0.34) | GAA | |
| SCHEMBL20170666 | 0.77 | GAA (0.37) | GAA | |
| SCHEMBL12944985 | 0.77 | GAA (0.38) | GAA | |
| SCHEMBL20170609 | 0.76 | NR3C1 (0.33) | GAA | |
| SCHEMBL20170664 | 0.75 | GAA (0.36) | GAA | |
| SCHEMBL20170756 | 0.71 | TRPV1 (0.34) | GAA | |
| SCHEMBL12646332 | 0.69 | OPRM1 (0.51) | GAA | |
| SCHEMBL22058060 | 0.68 | GAA (0.34) | GAA | |
| SCHEMBL18458096 | 0.68 | GAA (0.44) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |