Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12945027 | 0.96 | GAA (0.38) | GAAOPRD1OPRM1OPRK1 | |
| SCHEMBL20170701 | 0.88 | GAA (0.39) | GAA | |
| SCHEMBL10222587 | 0.88 | GAA (0.39) | GAAOPRD1 | |
| SCHEMBL12944985 | 0.88 | GAA (0.38) | GAAOPRD1OPRM1OPRK1 | |
| SCHEMBL10222583 | 0.87 | OPRM1 (0.33) | GAAOPRD1OPRM1OPRK1 | |
| SCHEMBL12945149 | 0.84 | GAA (0.36) | GAAOPRD1OPRM1OPRK1 | |
| SCHEMBL20170807 | 0.83 | GAA (0.48) | GAAOPRD1OPRM1OPRK1 | |
| SCHEMBL12945098 | 0.83 | GAA (0.37) | GAAOPRD1OPRM1OPRK1 | |
| SCHEMBL12945025 | 0.82 | GAA (0.38) | GAA | |
| SCHEMBL20170840 | 0.77 | GAA (0.41) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |