Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2618327 | 1.00 | NR3C1 (0.64) | NR3C1GLUL | |
| SCHEMBL2631126 | 1.00 | NR3C1 (0.64) | NR3C1GLUL | |
| SCHEMBL1880341 | 0.94 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL12956252 | 0.94 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL12671487 | 0.94 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL12956597 | 0.85 | NR3C1 (0.61) | NR3C1GLUL | |
| SCHEMBL13049218 | 0.85 | NR3C1 (0.61) | NR3C1GLUL | |
| SCHEMBL13376688 | 0.84 | NR3C1 (0.68) | NR3C1GLUL | |
| SCHEMBL12023015 | 0.84 | NR3C1 (0.71) | NR3C1GLUL | |
| SCHEMBL13376552 | 0.84 | NR3C1 (0.68) | NR3C1GLUL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338472-B2 | Hexahydrocyclopentyl[F]indazole carboxamides and derivatives thereof as selective glucocorticoid receptor modulators | MERCK SHARP & DOHME CORP. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20110003797-A1 | HEXAHYDROCYCLOPENTYL[f]INDAZOLE CARBOXAMIDES AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS | MERCK & CO., INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003797-A1 | HEXAHYDROCYCLOPENTYL[f]INDAZOLE CARBOXAMIDES AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, NR3C2, GRK5 | NR3C1 1/4885GLUL 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.