Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.87 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.74 |
| ▸ | OSBP | P22059 | 3/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | RORC | P51449 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.70 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.69 |
| ▸ | GBA1 | P04062 | 2/20 | 0.63 |
| ▸ | UGCG | Q16739 | 2/20 | 0.63 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.60 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15398207 | 1.00 | POLA1 (0.87) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL14828594 | 0.95 | POLA1 (0.78) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL587902 | 0.93 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL15110118 | 0.93 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL587901 | 0.93 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL13147079 | 0.93 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL1708156 | 0.93 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL16306859 | 0.93 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL12919627 | 0.92 | POLA1 (0.86) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL12192374 | 0.92 | POLA1 (0.79) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170112800-A1 | SUPRAMOLECULAR COMBINATORIAL THERAPEUTICS | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2017-04-27 | — | — | US | disclosed |
| US-20160145284-A1 | LIPID-BASED PLATINUM COMPOUNDS AND NANOPARTICLES | INVICTUS ONCOLOGY PVT. LTD. (IN) | 2016-05-26 | — | — | US | disclosed |
| US-8653049-B2 | Normuramyl glycopeptide compounds | IMUTHES LIMITED (GB) | 2014-02-18 | — | — | US | disclosed |
| EP-2578598-A1 | Componds derived from normuramyldipeptide | IMUTHES LIMITED (GB) | 2013-04-10 | — | — | EP | disclosed |
| US-20110002983-A1 | COMPOUND | IMUTHES LIMITED (GB) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112800-A1 | SUPRAMOLECULAR COMBINATORIAL THERAPEUTICS | PDCD1LG2, PDCD1, ERBB3 | POLA1 3019/4885CYP46A1 2429/4885OSBP 2179/4885 |
| US-20160145284-A1 | LIPID-BASED PLATINUM COMPOUNDS AND NANOPARTICLES | SGMS1, SGMS2, PHOSPHO1 | POLA1 2085/4885CYP46A1 1184/4885OSBP 645/4885 |
| US-20110002983-A1 | COMPOUND | C5AR1, C5AR2, ARG1 | POLA1 3132/4885CYP46A1 265/4885OSBP 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.