Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 3/20 | 1.00 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.74 |
| ▸ | OSBP | P22059 | 3/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | RORC | P51449 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.70 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.69 |
| ▸ | CDC25A | P30304 | 1/20 | 0.64 |
| ▸ | GBA1 | P04062 | 2/20 | 0.63 |
| ▸ | UGCG | Q16739 | 2/20 | 0.63 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.63 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110118 | 1.00 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL587902 | 1.00 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL16306859 | 1.00 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL13147079 | 1.00 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL1708156 | 1.00 | POLA1 (1.00) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL15398207 | 0.93 | POLA1 (0.87) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL12947846 | 0.93 | POLA1 (0.87) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL5009864 | 0.93 | POLA1 (0.86) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL16790328 | 0.93 | POLA1 (0.86) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL2474688 | 0.93 | POLA1 (0.86) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478709-A | Long-acting hepatitis virus entry inhibitor | 成都奥达生物科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114478744-A | Long-acting GLP-1 antagonist | 成都奥达生物科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-111777671-A | Long-acting PSD-95 inhibitor | 成都奥达生物科技有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-111675752-A | Coronavirus membrane fusion inhibitor and pharmaceutical application thereof | 成都奥达生物科技有限公司 | 2020-09-18 | — | — | CN | claimed |
| CN-111285923-A | PSD-95 inhibitor | 成都奥达生物科技有限公司 | 2020-06-16 | — | — | CN | claimed |
| CN-110627877-A | PSD-95 inhibitor | 成都奥达生物科技有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-111285923-B | PSD-95 inhibitor | 成都奥达生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114478744-A | Long-acting GLP-1 antagonist | 成都奥达生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478709-A | Long-acting hepatitis virus entry inhibitor | 成都奥达生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2020249745-A1 | CATIONIC MICELLES AND METHODS FOR USING THEM | DANMARKS TEKNISKE UNIVERSITET (DK) | 2020-12-17 | — | — | WO | disclosed |
| CN-111777671-A | Long-acting PSD-95 inhibitor | 成都奥达生物科技有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-111675752-A | Coronavirus membrane fusion inhibitor and pharmaceutical application thereof | 成都奥达生物科技有限公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-111285923-A | PSD-95 inhibitor | 成都奥达生物科技有限公司 | 2020-06-16 | — | — | CN | disclosed |
| US-20120089222-A1 | Photo-Activated Attachment Of Cholesterol To Polyurethane Surfaces For Adhesion Of Endothelial Cells | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2012-04-12 | — | — | US | disclosed |
| EP-2416658-A1 | PHOTO-ACTIVATED ATTACHMENT OF CHOLESTEROL TO POLYURETHANE SURFACES FOR ADHESION OF ENDOTHELIAL CELLS | The Children's Hospital Of Philadelphia (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20110200582-A1 | LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM | NOVARTIS AG (CH) | 2011-08-18 | — | — | US | disclosed |
| US-20110200582-A1 | LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM | NOVARTIS AG (CH) | 2011-08-18 | — | — | US | disclosed |
| WO-2010118306-A1 | PHOTO-ACTIVATED ATTACHMENT OF CHOLESTEROL TO POLYURETHANE SURFACES FOR ADHESION OF ENDOTHELIAL CELLS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2010-10-14 | — | — | WO | disclosed |
| EP-1706415-A1 | LIPID- DERIVATIZED BISPHOSPHONIC ACID | MCS Micro Carrier Systems GmbH (DE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005070952-A1 | LIPID- DERIVATIZED BISPHOSPHONIC ACID | MCS MICRO CARRIER SYSTEMS GMBH (DE) | 2005-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110200582-A1 | LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM | SGMS1, SGMS2, LIPC | POLA1 4444/4885CYP46A1 92/4885OSBP 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.