Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIP | O00170 | 1/20 | 0.54 |
| ▸ | SGTA | O43765 | 1/20 | 0.54 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.54 |
| ▸ | STIP1 | P31948 | 1/20 | 0.54 |
| ▸ | PPP5C | P53041 | 1/20 | 0.54 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.54 |
| ▸ | PPID | Q08752 | 1/20 | 0.54 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.54 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.54 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.54 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.54 |
| ▸ | AIPL1 | Q9NZN9 | 1/20 | 0.54 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004825 | 0.87 | AIP (0.56) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL8004264 | 0.67 | GRIN2C (0.48) | ALDH1A1HPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL1006092 | 0.67 | ALDH1A1 (0.54) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL1009791 | 0.66 | AIP (0.52) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL7003055 | 0.62 | AIP (0.74) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL11324603 | 0.62 | AIP (0.66) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL7002920 | 0.62 | AIP (0.70) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL1889692 | 0.62 | AIP (0.46) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL3453384 | 0.62 | LMNA (0.64) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8004237 | 0.60 | HDAC4 (0.49) | KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269990-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |