Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.69 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.69 |
| ▸ | CCR3 | P51677 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953791 | 0.91 | CHRM3 (0.67) | CHRM2CHRM1CHRM3CCR3CCR1 | |
| SCHEMBL12953549 | 0.88 | CHRM3 (0.65) | CHRM2CHRM1CHRM3 | |
| SCHEMBL138459 | 0.82 | CHRM3 (1.00) | CHRM2CHRM1CHRM3CCR3 | |
| SCHEMBL138458 | 0.82 | CHRM3 (1.00) | CHRM2CHRM1CHRM3CCR3 | |
| SCHEMBL12954109 | 0.80 | CHRM3 (0.60) | CHRM2CHRM1CHRM3 | |
| SCHEMBL12953389 | 0.78 | CHRM2 (0.66) | CHRM2CHRM1CHRM3 | |
| SCHEMBL12954023 | 0.78 | CHRM3 (0.44) | CHRM2CHRM1CHRM3 | |
| SCHEMBL12953184 | 0.78 | CHRM3 (0.47) | CHRM2CHRM1CHRM3CCR1 | |
| SCHEMBL12953201 | 0.77 | CHRM3 (0.60) | CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL12954020 | 0.75 | CHRM3 (0.62) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677795-B1 | MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2011-01-05 | — | — | EP | disclosed |