Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.67 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12954024 | 0.91 | CHRM2 (0.69) | CHRM3CHRM1CHRM2CCR3CCR1 | |
| SCHEMBL12953549 | 0.89 | CHRM3 (0.65) | CHRM3CHRM1CHRM2ATML3MBTL1 | |
| SCHEMBL12954109 | 0.81 | CHRM3 (0.60) | CHRM3CHRM1CHRM2ATML3MBTL1 | |
| SCHEMBL14401582 | 0.80 | CHRM3 (1.00) | CHRM3CHRM1CHRM2 | |
| SCHEMBL136414 | 0.80 | CHRM3 (1.00) | CHRM3CHRM1CHRM2 | |
| SCHEMBL136415 | 0.80 | CHRM3 (1.00) | CHRM3CHRM1CHRM2 | |
| SCHEMBL12953389 | 0.79 | CHRM2 (0.66) | CHRM3CHRM1CHRM2L3MBTL1 | |
| SCHEMBL12954023 | 0.79 | CHRM3 (0.44) | CHRM3CHRM1CHRM2ATML3MBTL1 | |
| SCHEMBL12953184 | 0.79 | CHRM3 (0.47) | CHRM3CHRM1CHRM2CCR1ATM | |
| SCHEMBL12953201 | 0.78 | CHRM3 (0.60) | CHRM3CHRM1CHRM2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677795-B1 | MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2011-01-05 | — | — | EP | disclosed |