Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.36 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953549 | 0.82 | CHRM3 (0.65) | CHRM2CHRM1CHRM3ALDH1A1L3MBTL1 | |
| SCHEMBL142015 | 0.80 | CHRM3 (1.00) | CHRM2CHRM1CHRM3CYP2C19GBA1 | |
| SCHEMBL142014 | 0.80 | CHRM3 (1.00) | CHRM2CHRM1CHRM3CYP2C19GBA1 | |
| SCHEMBL12954023 | 0.80 | CHRM3 (0.44) | CHRM2CHRM1CHRM3L3MBTL1 | |
| SCHEMBL12954109 | 0.80 | CHRM3 (0.60) | CHRM2CHRM1CHRM3L3MBTL1 | |
| SCHEMBL12953791 | 0.79 | CHRM3 (0.67) | CHRM2CHRM1CHRM3L3MBTL1 | |
| SCHEMBL12954024 | 0.78 | CHRM2 (0.69) | CHRM2CHRM1CHRM3 | |
| SCHEMBL12953202 | 0.76 | CHRM3 (0.45) | CHRM2CHRM1CHRM3CYP2C19KCNH2 | |
| SCHEMBL13187336 | 0.76 | CHRM3 (0.42) | CHRM2CHRM1CHRM3CYP2C19KCNH2 | |
| SCHEMBL12953184 | 0.75 | CHRM3 (0.47) | CHRM2CHRM1CHRM3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677795-B1 | MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2011-01-05 | — | — | EP | disclosed |