⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2149222 | 0.79 | — | — | |
| SCHEMBL22685773 | 0.74 | — | — | |
| SCHEMBL17245051 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL108395 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL133571 | 0.66 | — | — | |
| SCHEMBL16072560 | 0.65 | PRKCA (0.38) | — | |
| SCHEMBL1295664 | 0.60 | — | — | |
| SCHEMBL20513938 | 0.59 | — | — | |
| SCHEMBL20513367 | 0.59 | — | — | |
| SCHEMBL17245048 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248568-A1 | NANO-CRYSTALLINE DENTAL CERAMICS | James R. Glidewell Dental Ceramics, Inc. (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-2382959-B1 | Nano-crystalline dental ceramics | GLIDEWELL JAMES R DENTAL CERAMICS INC (US) | 2017-08-09 | — | — | EP | disclosed |
| US-8298329-B2 | Nano-crystalline dental ceramics | JAMES R. GLIDEWELL DENTAL CERAMICS, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-20110269618-A1 | NANO-CRYSTALLINE DENTAL CERAMICS | JAMES R. GLIDEWELL DENTAL CERAMICS, INC. | 2011-11-03 | — | — | US | disclosed |
| EP-2382959-A2 | Nano-crystalline dental ceramics | James R. Glidewell Dental Ceramics, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20090320771-A1 | IONIC LIQUID MEDIUMS FOR HOLDING SOLID PHASE PROCESS GAS PRECURSORS | MATHESON TRI-GAS (US) | 2009-12-31 | — | — | US | disclosed |