Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23664521 | 0.88 | CASP2 (0.47) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL13461485 | 0.87 | CASP2 (0.54) | CASP2NAAAFAAHMMP2MMP9 | |
| SCHEMBL25715319 | 0.87 | NOD1 (0.63) | EPHX2SLC6A5NOD1 | |
| SCHEMBL21686255 | 0.87 | NOD1 (0.63) | EPHX2SLC6A5NOD1 | |
| SCHEMBL8210240 | 0.85 | CASP2 (0.59) | CASP2NAAAFAAHMMP2MMP9 | |
| SCHEMBL15783568 | 0.83 | CASP2 (0.56) | CASP2NAAAMMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL23834203 | 0.82 | CASP2 (0.54) | CASP2NAAAMMP2MMP9MMP8 | |
| SCHEMBL24119974 | 0.80 | NOD1 (0.45) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL23463505 | 0.79 | ALDH1A1 (0.38) | CASP2NAAANOD1 | |
| SCHEMBL26773565 | 0.79 | NAMPT (0.41) | CASP2NAAAFAAHDNM1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578778-B1 | GHRELIN ANALOGS | IPSEN PHARMA (FR) | 2011-01-26 | — | — | EP | disclosed |