Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 4/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | RHOC | P08134 | 2/20 | 0.37 |
| ▸ | RHOA | P61586 | 2/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1295918 | 0.87 | RXRA (0.41) | IDO1CES2DAORXRARXRB | |
| SCHEMBL5592016 | 0.86 | NOTUM (0.41) | IDO1CES2DAOLMNAMTOR | |
| SCHEMBL23536705 | 0.86 | IDH1 (0.39) | IDO1DAO | |
| SCHEMBL22783327 | 0.86 | IDO1 (0.37) | IDO1CES2DAOLMNAACP3 | |
| SCHEMBL5264172 | 0.86 | IDO1 (0.41) | IDO1CES2DAORHOCRHOA | |
| SCHEMBL1838112 | 0.80 | DAO (0.45) | IDO1CES2DAOLMNARXRA | |
| SCHEMBL15542278 | 0.80 | CYP3A4 (0.42) | IDO1LMNA | |
| SCHEMBL27998583 | 0.79 | IDO1 (0.47) | IDO1CES2DAOLMNARXRA | |
| SCHEMBL28869017 | 0.79 | IDO1 (0.47) | IDO1CES2DAORXRARXRB | |
| SCHEMBL39835 | 0.79 | TAAR1 (0.56) | IDO1CES2DAOLMNAACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970927-A1 | IMMOBILIZED KETOREDUCTASES AND PROCESS FOR MAKING AND USING IMMOBILIZED KETOREDUCTASE | Merck Sharp & Dohme Corp. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014150633-A1 | IMMOBILIZED KETOREDUCTASES AND PROCESS FOR MAKING AND USING IMMOBILIZED KETOREDUCTASE | MERCK SHARP & DOHME CORP. (US) | 2014-09-25 | — | — | WO | claimed |
| EP-1828391-A2 | PROCESS FOR THE SYNTHESIS OF (S)-1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-OL | Merck & Co., Inc. (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006065840-A2 | PROCESS FOR THE SYNTHESIS OF (S)-1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-OL | MERCK & CO., INC. (US) | 2006-06-22 | — | — | WO | claimed |
| EP-1345878-A4 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | MERCK & CO INC (US) | 2005-12-14 | — | — | EP | claimed |
| EP-1345878-A1 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | Merck & Co., Inc. (US) | 2003-09-24 | — | — | EP | claimed |
| EP-1192118-A4 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | MERCK & CO INC (US) | 2002-11-04 | — | — | EP | claimed |
| WO-2002050009-A1 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | MERCK & CO., INC. (US) | 2002-06-27 | — | — | WO | claimed |
| EP-1196364-A1 | PROCESS FOR THE SYNTHESIS OF (R)-1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-OL BY ASYMMETRIC TRANSFER HYDROGENATION | Merck & Co., Inc. (US) | 2002-04-17 | — | — | EP | claimed |
| EP-1192118-A1 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | Merck & Co., Inc. (US) | 2002-04-03 | — | — | EP | claimed |
| WO-2001002326-A1 | PROCESS FOR THE SYNTHESIS OF (R)-1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-OL BY ASYMMETRIC TRANSFER HYDROGENATION | MERCK & CO., INC. (US) | 2001-01-11 | — | — | WO | claimed |
| WO-2000076948-A1 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | MERCK & CO., INC. (US) | 2000-12-21 | — | — | WO | claimed |
| CN-113388627-B | Reductase LX05 gene, genetic engineering bacterium containing gene and application of gene | 湖南科技大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-113388627-A | Reductase LX05 gene, genetic engineering bacterium containing gene and application of gene | 湖南科技大学 | 2021-09-14 | — | — | CN | disclosed |
| CN-108441433-B | Rhodotorula mucilaginosa NQ1 and application thereof in preparation of chiral alcohol | 湖南科技大学 | 2021-08-20 | — | — | CN | disclosed |
| CN-108441433-B | Rhodotorula mucilaginosa NQ1 and application thereof in preparation of chiral alcohol | 湖南科技大学 | 2021-08-20 | — | — | CN | disclosed |
| WO-2001074829-A1 | RUTHENIUM-DIPHOSPHINE COMPLEXES AND THEIR USE AS CATALYSTS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2001-10-11 | — | — | WO | disclosed |
| WO-2001032656-A1 | POLYMORPHIC FORM OF A TACHYKININ RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 2001-05-10 | — | — | WO | disclosed |
| WO-2001002326-A1 | PROCESS FOR THE SYNTHESIS OF (R)-1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-OL BY ASYMMETRIC TRANSFER HYDROGENATION | MERCK & CO., INC. (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2000076948-A1 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | MERCK & CO., INC. (US) | 2000-12-21 | — | — | WO | disclosed |