Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862215 | 0.88 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL12957311 | 0.88 | METTL3 (0.43) | ALDH1A1TDP1METTL3 | |
| SCHEMBL12957423 | 0.84 | METTL3 (0.42) | ALDH1A1HTTLMNATDP1MEN1 | |
| SCHEMBL11956925 | 0.81 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL13472097 | 0.81 | METTL3 (0.49) | METTL3 | |
| SCHEMBL13250854 | 0.81 | METTL3 (0.49) | METTL3 | |
| SCHEMBL11956950 | 0.80 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL11956943 | 0.77 | — | — | |
| SCHEMBL13862191 | 0.76 | — | — | |
| SCHEMBL14611649 | 0.74 | METTL3 (0.42) | ALDH1A1HTTLMNATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272516-A2 | 4-Oxoquinoline compound and use thereof as HIV integrase inhibitor | Japan Tobacco, Inc. (JP) | 2011-01-12 | — | — | EP | disclosed |