Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21936494 | 0.80 | AR (0.47) | ARPGR | |
| SCHEMBL12960442 | 0.78 | AR (0.45) | ARPGR | |
| SCHEMBL18856260 | 0.74 | AR (0.51) | ARPGR | |
| SCHEMBL4404032 | 0.74 | AR (0.51) | ARPGR | |
| SCHEMBL4402110 | 0.74 | AR (0.51) | ARPGR | |
| SCHEMBL16130164 | 0.73 | AR (0.50) | ARPGR | |
| SCHEMBL1190703 | 0.72 | AR (0.49) | ARPGR | |
| SCHEMBL189787 | 0.72 | AR (0.49) | ARPGR | |
| SCHEMBL10297754 | 0.71 | AR (0.71) | ARPGR | |
| SCHEMBL22834021 | 0.71 | AR (0.47) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963026-B1 | SUBSTITUTED (R)-3-(4-METHYLCARBAMOYL-3-FLUOROPHENYLAMINO)TETRAHYDROFURAN-3-ENECARBOXYLIC ACID (VARIANTS) AND ESTER THEREOF, METHOD FOR PRODUCING AND USING SAME | R PHARM INT LLC (RU) | 2020-04-29 | — | — | EP | disclosed |