Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929971 | 0.86 | ATM (0.44) | ATMKDM4ECALM1STAT3ALOX5 | |
| SCHEMBL18924620 | 0.83 | KDM4E (0.42) | ATMKDM4EMAPK1ALDH1A1CYP19A1 | |
| SCHEMBL22838628 | 0.83 | TTR (0.42) | POLBNPC1RAB9ATSHRCYP3A4 | |
| SCHEMBL25687627 | 0.80 | ALDH1A1 (0.61) | KDM4EALOX5GABRA1GABRB2NPC1 | |
| SCHEMBL10175139 | 0.77 | HDAC4 (0.43) | POLBSMN1; SMN2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL10172021 | 0.77 | CA12 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11437277 | 0.77 | CA12 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2632721 | 0.77 | ACHE (0.50) | KDM4EPOLBNPC1RAB9AMAPK1 | |
| SCHEMBL12606793 | 0.77 | CA12 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL427541 | 0.76 | ATM (0.68) | ATMKDM4ESTAT3POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | FLI1, VGF, GMFG | ATM 1893/4885KDM4E 982/4885CALM1 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.